Prof. Chan graduated from Dentistry (DMD, Cum Laude & Valedictorian 1981) and Medicine (MD, 1985) respectively from University of the East, Philippines and is currently both a registered dentist and medical doctor in Hong Kong. He joined the Department of Pediatrics of the University of Hong Kong in 1989. Then he pursued further training at the St. Jude Children’s Research Hospital, USA as a fellow from 1993 to 1996. He then obtained Dip of Palliative Medicine (1997) from University of Wales and MSc from University of Birmingham (1999). He joined the Faculty of Medicine, University of Hong Kong as Clinical Associate Professor in 1999, and was appointed as the Assistant Dean (External Affair) of the LKS Faculty of Medicine from 2004 to 2013. He was promoted to Clinical Professor in 2009. Since 2012, he has been the Head & Chief of Service of the Department of Paediatrics & Adolescent Medicine, Queen Mary Hospital & HKU-Shenzhen Hospital, The University of Hong Kong. He was awarded Tsao Yen-Chow Endowed Professorship of Pediatrics & Adolescent Medicine in 2013. He is currently the Director of the Molecular Laboratory for Traditional Chinese Medicine, HKU. He was appointed as the Chief of Service and Service Head of Pediatric Oncology for The Hong Kong Children’s Hospital since Oct 2018. He supervised >50 MSc & PhD students and published >300 full articles, 10 book chapters and 1 book. (H Index 42, total citation >6000) He serves as editor for 12 journals and is the immediate past Chief Editor of Hong Kong Journal of Paediatrics. He received multiple prestigious research grants with a total amount over US$ 6millions. He owned 5 patents including 3 on collagen microsphere device for the delivery of human mesenchymal stem cells. He has multiple International Awards (ANR, SIOP, ASPR, Endeavor Executive Award-Australian Government, Outstanding Pediatrician of APPA) for his clinical and laboratory research works on childhood neurogenic tumors and stem cells biology. His research interest includes the immunological aspects of stem cells, cancers and thalassemia. He is the Immediate Past Chairman of St Jude- VIVA-Asia Pediatric BMT Consortium, Regional Chairman (Asia, Australia & Africa) of Advance in Neuroblastoma Research, Secretary of the Asian Pediatric Hematology Oncology Group, and is the Immediate Past President of Hong Kong Pediatric Society.